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A spreading rash over the body is a hallmark symptom of measles. Measles typically begins with initial symptoms such as fever, cough, runny nose, and conjunctivitis, followed by the characteristic rash that usually appears several days later. The rash often starts at the hairline, spreads to the face, and then continues down the body. This progression is significant in identifying measles, as the rash serves as a key indicator of the disease's presence.

The other symptoms mentioned, while they may occur with different illnesses, are not specific indicators of measles. Severe abdominal pain is not commonly associated with measles, extreme fatigue is too vague and can apply to many health conditions, and a sore throat is also a symptom of various respiratory infections unrelated to measles. Understanding the specifics of each disease is crucial for accurate identification and treatment.