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The primary mode of transmission for anthrax is through airborne particles. Anthrax is caused by the bacterium Bacillus anthracis, which can form spores that are resistant to extreme conditions. These spores can be aerosolized, meaning they can become airborne, especially in environments like agricultural areas where animals infected with anthrax may be present. When inhaled, these spores can cause inhalational anthrax, a serious and often fatal form of the disease.

While anthrax can also be transmitted through contaminated food (such as undercooked meat from infected animals) or through direct contact with contaminated materials (like animal hides), inhalation is the most potent transmission route in terms of severity and potential public health impact. Insects generally do not play a significant role in the transmission of anthrax to humans.